Jump to navigation. To apply for scholarship, please provide the following documentation along with the registration form:. El Sistema Somerville is a daily afterschool music program that provides ensemble-based music instruction to SPS elementary and middle grades students, grades 3—8. The program offers intensive study on strings, winds and brass instruments through orchestral rehearsals, sectionals, musicianship and technique classes, chamber music, and private lessons. Students play violin, viola, cello, bass, flute, clarinet, saxophone, trumpet, and trombone.
Students also receive a daily nutritious snack, academic support, recess time, cultural enrichment activities, field trips, and frequent opportunities to perform for the community. The program meets Mondays-Fridays from p. At El Sistema Somerville, it is our mission to empower all students to become confident, engaged learners through rigorous, daily instruction in music ensembles and to provide the community with equitable access to musical excellence.
Teamwork : In music ensembles, all musicians maintain the same goal - to make beautiful music as a team. Commitment : Students will strive towards and achieve success by participating and engaging fully in all ensembles and persevering even when things get tough.
Respect : Students will demonstrate care and appreciation for their peers, teachers, instruments and materials. Communication : Students will develop their ability to express their thoughts, feelings and ideas in a calm and confident manner. Empathy : Students will enhance their capabilities of being sensitive to how their actions can affect others, celebrating with others during joyful times or comforting others during challenging times.
Venezuela's national youth orchestra program, known as El Sistema, inspired our program. Founded in by Dr. Jose Antonio Abreu, an economist and composer, El Sistema is recognized around the globe for providing intense, rigorous musical education that positively alters the life trajectories of many underserved students.
Watch Dr. Jose Antonio Abreu explain equitable access to high-quality music education in his Ted Talk. El Sistema.In postmenopausal women and elderly men, bone density decreases with age and vascular calcification is aggravated.
This condition is closely associated with vitamin K2 deficiency. For instance, carboxylated osteocalcin is beneficial for bone and aids the deposition of calcium into the bone matrix. Carboxylated matrix Gla protein effectively protects blood vessels and may prevent calcification within the vascular wall.
In addition, periostin may promote the differentiation, aggregation, adhesion and proliferation of osteoblasts. Periostin also occurs in the heart and may be associated with the reconstruction of heart function. Both the bone and cardiovascular system are closely associated during embryonic development.
Thus, the present study hypothesized that embryonic developmental position and tissue calcification may have a certain association for the bone and the cardiovascular system.
The results of the review suggest that the vascular calcification and osteogenic differentiation of vascular smooth muscle cells may be associated with the location of the bone and cardiovascular system during embryonic development. Abstract In postmenopausal women and elderly men, bone density decreases with age and vascular calcification is aggravated. Publication types Review. Substances Vitamin K.The Elo [a] rating system is a method for calculating the relative skill levels of players in zero-sum games such as chess.
It is named after its creator Arpad Eloa Hungarian-American physics professor. The Elo system was originally invented as an improved chess-rating system over the previously used Harkness systembut is also used as a rating system for multiplayer competition in a number of video games association footballAmerican footballbasketball Major League Baseballtable tennisboard games such as Scrabble and Diplomacyand other games.
The difference in the ratings between two players serves as a predictor of the outcome of a match. Two players with equal ratings who play against each other are expected to score an equal number of wins. A player's Elo rating is represented by a number which may change depending on the outcome of rated games played. After every game, the winning player takes points from the losing one.
The difference between the ratings of the winner and loser determines the total number of points gained or lost after a game. If the high-rated player wins, then only a few rating points will be taken from the low-rated player. However, if the lower-rated player scores an upset winmany rating points will be transferred. The lower-rated player will also gain a few points from the higher rated player in the event of a draw. This means that this rating system is self-correcting. Players whose ratings are too low or too high should, in the long run, do better or worse correspondingly than the rating system predicts and thus gain or lose rating points until the ratings reflect their true playing strength.
An Elo rating is a comparative rating only, and is valid only within the rating pool where it was established.
The Harkness system was reasonably fair, but in some circumstances gave rise to ratings which many observers considered inaccurate. Elo's system replaced earlier systems of competitive rewards with a system based on statistical estimation.
Rating systems for many sports award points in accordance with subjective evaluations of the 'greatness' of certain achievements. For example, winning an important golf tournament might be worth an arbitrarily chosen five times as many points as winning a lesser tournament. A statistical endeavor, by contrast, uses a model that relates the game results to underlying variables representing the ability of each player. Elo's central assumption was that the chess performance of each player in each game is a normally distributed random variable.
Although a player might perform significantly better or worse from one game to the next, Elo assumed that the mean value of the performances of any given player changes only slowly over time. Elo thought of a player's true skill as the mean of that player's performance random variable.
Vitamin K‑dependent proteins involved in bone and cardiovascular health (Review)
A further assumption is necessary because chess performance in the above sense is still not measurable. One cannot look at a sequence of moves and derive a number to represent that player's skill.
Performance can only be inferred from wins, draws and losses. Therefore, if a player wins a game, they are assumed to have performed at a higher level than their opponent for that game.Sistema is heavily focused on cooperation and partnerships with leading multinational and Russian companies.
Always open to discussing potential co-investment projects, it will become a reliable partner for your business. Real Estate. Industrial production. Sistema VC. Sistema Asia Fund. Sistema Capital. Map of industries. Financial results. One of the largest private investors in the Russian economy with a unique portfolio of assets in various sectors. Assets All assets. Retail Detsky Mir Industrial production Segezha Group Collective investment Sistema Capital Company Details.
Retail business via a digital platform. Stock prices GDRs of Sistema. Shares of Sistema. Shares of MTS. New York Stock Exchange.
Shares of Detsky Mir.The mission of El Sistema Oklahoma is to serve the community by engaging children within an ensemble based music program so they can share the joy of music making and grow as responsible and productive citizens. The announcement on Broadway World notes: "El Sistema Oklahoma has grown rapidly into a well respected, successful after school program that engages more than public school children in the heart of Oklahoma City.
The mission of El Sistema Oklahoma is to serve the community by engaging children in an ensemble based music program so they can share the joy of music making and grow as responsible citizens. El Sistema Oklahoma is a c3 charitable organization. Your tax-deductible donations can be made directly to ESO or through our designated fund at St.
Luke's United Methodist Church. Learn more. Experience our children's outstanding concert performances and learn more about El Sistema Oklahoma. Home The mission of El Sistema Oklahoma is to serve the community by engaging children within an ensemble based music program so they can share the joy of music making and grow as responsible and productive citizens. We are a c3!The role of vitamin K in the nervous system has been somewhat neglected compared with other physiological systems despite the fact that this nutrient was identified some 40 y ago as essential for the synthesis of sphingolipids.
Present in high concentrations in brain cell membranes, sphingolipids are now known to possess important cell signaling functions in addition to their structural role.
In the past 20 y, additional support for vitamin K functions in the nervous system has come from the discovery and characterization of vitamin K—dependent proteins that are now known to play key roles in the central and peripheral nervous systems. Notably, protein Gas6 has been shown to be actively involved in cell survival, chemotaxis, mitogenesis, and cell growth of neurons and glial cells.
Although limited in number, studies focusing on the relationship between vitamin K nutritional status and behavior and cognition have also become available, pointing to diet and certain drug treatments i. This review presents an overview of the research that first identified vitamin K as an important nutrient for the nervous system and summarizes recent findings that support this notion.
One of these, Gas6, was discovered in and has been closely associated with the nervous system 12. However, a role for vitamin K in this system that well predates the discovery of Gas6 is that in sphingolipid synthesis, a class of lipids present in high concentrations in both neuronal and glial cell membranes 3. In a series of publications that spanned from throughLev and colleagues 45 provided evidence that vitamin K modulates the activities of key enzymes of the sphingolipid biosynthetic pathway and hence their synthesis and metabolism.
Research conducted in more recent decades has generated data that confirm the relevance of vitamin K in the nervous system and cognition.
Notably, a strong relationship has been established between the K vitamers and sphingolipids in the brain and their modulation by nutritional status. Important findings have also been obtained with respect to the cell signaling actions of protein Gas6 in both the central and peripheral nervous systems. New knowledge has been gained about menaquinone-4 MK-4the principal K vitamer in brain, which could have far-reaching effects in the brain and other components of the nervous system.
Finally, a limited number of studies have provided evidence of a relationship between vitamin K status, behavior, and cognition.
Reports published in the past 2 decades confirmed the presence of vitamin K in the brain. However, although in the majority of extrahepatic tissues, vitamin K is present as phylloquinone K 1 and MK-4, vitamin K in the brain occurs predominantly as MK-4 67. In a detailed assessment of the anatomic distribution of vitamin K, MK-4 was present in all brain regions, although concentrations differed according to regions. Specifically, MK-4 was observed in highest concentrations in the midbrain and pons medulla and in lowest concentrations in the cerebellum, olfactory bulb, thalamus, hippocampus, and striatum 8.
Concentrations of MK-4 in the brain have also been shown to be affected by sex and age. In a study conducted in Brown Norway rats, MK-4 levels in the cortex and cerebellum were higher in female than in male rats despite similar diets, and concentrations decreased between 12 and 24 mo of age 7.
Vitamin K concentrations in the brain are also influenced by diet in a manner that reflects intake.
Sistema CGS de unidades
Sphingolipids are a group of complex lipids present in all mammalian cells where they are major components of cell membranes. They are present in particularly high concentrations in cells of the central and peripheral nervous systems with the major sphingolipids consisting of ceramide, sphingomyelin, cerebroside, sulfatide, and ganglioside 8.
As discussed below, certain sphingolipids are highly correlated with MK-4 in the brain. A simplified scheme of the sphingolipid biosynthetic pathways is presented in Fig.
A simplified scheme of sphingolipid pathways. CerDase, ceramidase; CerS, ceramide synthase; GalCeramidase, galactosylceramidase; GalCer sulfotransferase, galactosyl sulfotransferase; Gal-T1, galactosyltransferase; GluCeramidase, glucosylceramidase; GluCer synthase, glucosylceramide synthase; Sial-T1, lactosylceramide synthase; SM synthase, sphingomyelin synthase; SMase, sphingomyelinase.
Adapted with permission from 9. Initially appreciated for their structural role, sphingolipids are now viewed as key players in important cellular events such as proliferation, differentiation, senescence, cell—cell interaction, and transformation K-array has combined its innovative audio with high-end lighting technology in the form of the Rail, a 1. And to adapt to a variety of needs, the line comes with a host of combinations to coverage a wide range of applications.
More information about the Rail line. For architectural reasons, a visually discreet audio system may be required to integrate seamlessly with the layout without compromising sound quality. We put careful thought into designing a sleek form factor taking into consideration shape, space and function, resulting in a delicate balance of durable materials and advanced technology. We created a portfolio complete with lightweight products that are easy to transportation and quick to setup optimizing logistics, space, labor costs and time.
Boasting an incredible size-to-weight ratio, the most important factors of our audio solutions' weight are design methods, materials and manufacturing technology. Our strategy consists of utilizing minimal components and certain lower-density materials like aluminum and steel. To provide complete versatility, these all-white solutions can be combined in any number of combinations and adapt to the needs of different venues and events to ensure seamless integration throughout. Users have full control with DALI-included versions that allow for individual management of the units including light dimming.
With a very extended frequency range the loudspeaker covers the entire audible spectrum without the need for a subwoofer ideal for when there are space constraints. This solution also significantly reduces the number of cables and minimizes number of amp channels for easy wiring and quick installations. There is also the possibility to add indirect lighting to the top of the unit of the models for complete lighting coverage. The Rail line provides a selection of different direct light distribution: Symmetric, to spread the light equally in all directions; Asymmetrical, where the light is directed sideways to one side of the vertical plane; Mini Spot, which creates a fixed spotlight; and Electrified Track, where magnetic spotlights are adjustable to point in the desired direction.
There is also the possibility to add indirect lighting to the top of the unit of the above mentioned models for complete lighting coverage. Another way to adapt a Rail specifically to your needs is with the different model setups utilizing dedicated mounting accessories.
Another way to adapt a Rail specifically to your needs is with the available mounting options with dedicated accessories.
The Pendant model is when the unit is surface mounted to the ceiling. A Semi-Flushed model reduces the visibility of the unit while the Flushed version is completely inlayed in the ceiling. A Suspended version provides a hanging option while the Applique version can be surface mounted to the wall. Other mounting options include corner Rails and T-models for a complete system setup. Rail K-array has combined its innovative audio with high-end lighting technology in the form of the Rail, a 1.
Find your distributor. Visually Discreet For architectural reasons, a visually discreet audio system may be required to integrate seamlessly with the layout without compromising sound quality.
Lightweight We created a portfolio complete with lightweight products that are easy to transportation and quick to setup optimizing logistics, space, labor costs and time. Full-Range Frequency Response With a very extended frequency range the loudspeaker covers the entire audible spectrum without the need for a subwoofer ideal for when there are space constraints.
Multiple Installation Options Another way to adapt a Rail specifically to your needs is with the different model setups utilizing dedicated mounting accessories.11 Hallar el valor de k para que el sistema tenga infinitas sangomasvax.space4
Download the Datasheet. Discover more about Rail family.